A graded county road provides access to the east Aravaipa Canyon Wilderness boundary. Creek crossings and seasonal road conditions may necessitate high-clearance or four-wheel-drive vehicles. Winter and summer flooding make the road impassable to all vehicles. Call ahead for road information.

To reach Turkey Creek, drive 15 miles northwest of Safford on Highway 70. Turn west on Aravaipa-Klondyke Road and go approximately 45 miles, passing through the town of Klondyke and The Nature Conservancy's Aravaipa Canyon Preserve, to the eastern boundary of the Aravaipa Canyon Wilderness. From there, continue on the road, which turns left up Turkey Creek.