Seedskadee National Wildlife Refuge (NWR) is located in southwestern Wyoming. The name Seedskadee originated from the Shoshone Indian word "Sisk-a-dee-agie" meaning "river of the prairie hen." The 26,400-acre Refuge protects a mosaic of riparian, wetland, and upland shrub habitats along 36 miles of the Green River. The river is an oasis that bisects the vast high desert sagebrush plains of southwest Wyoming. Seedskadee NWR was established in 1965 as mitigation for the loss of habitat when Flaming Gorge and Fontenelle dams were constructed. The riparian corridor is an important migration route and nesting area for a wide variety of migratory waterfowl and passerine bird species. Refuge lands are rich in historic and cultural resources because the area was used by nomadic Indian tribes, fur trappers, and early pioneers. Today, approximately 10,000 people visit the Refuge annually, and more than 20 educational and civic organizations participate in environmental education or volunteer programs.

From Green River, Wyoming, travel west on I-80 about 6 miles to the La Barge Road (Highway 372) exit. Continue north about 27 miles on Highway 372 to the main entrance sign for the Refuge. Turn right onto the gravel entrance road and travel 2.5 miles to the Refuge headquarters. The Refuge is located approximately 1 hour from the Rock Springs airport, 3 hours east of the Salt Lake City Airport, or 3 hours south of the Jackson, Wyoming airport.