Located midway on the Georgia coastline on the eastern fringe of McIntosh County, Sapelo Island is defined by the Sapelo River to the north, the waters of Doboy Sound to the south, the Atlantic Ocean to the east, and the Duplin River to the west. The 16,500 acre island is the 4th largest barrier island in the State of Georgia. Sapelo Island is accessed by means of a scheduled public ferry.

The Sapelo Island National Estuarine Research Reserve (SINERR), located on the western perimeter of Sapelo, is dedicated to research, education, stewardship, and sound management of coastal resources in Georgia. Specifically, we focus on the natural, cultural, and historical resources of Sapelo Island and the Duplin River estuary.

The reserve is seven and half miles northeast of Darien, Ga.