Welcome to Panther Swamp National Wildlife Refuge ... one of seven refuges in the Theodore Roosevelt National Wildlife Refuge Complex. Established in 1978, Panther Swamp National Wildlife Refuge encompasses 38,697 acres. Included in those acres is one of the largest blocks (21,000 acres) of bottomland forest in the lower Mississippi River alluvial floodplain. The upland areas or ridges often crest at no more than one foot above swamp areas, and contain nuttall, willow and water oaks and other species while overcup oak, bitter pecan and ash dominate the transition zone from swamp to upland. Additional habitat types consist of reforested and agricultural areas. In addition to providing resting and feeding areas for over 100,000 wintering waterfowl annually, the refuge also provides habitat for 200 species of neotropical migratory songbirds. Resident species making their home among the woodlands, sloughs, and reforested areas include the American alligator, white-tail deer, otter, swamp rabbit, wild turkey, squirrel, and other various small fur-bearers such as mink and raccoon.

Panther Swamp National Wildlife Refuge is located ten miles southwest of Yazoo City, Mississippi. From Yazoo City, take MS Highway 149W across the Yazoo River bridge, then take the first paved road to the left (River Road). Travel approximately 7 miles to a gravel road where the refuge Headquarters sign is located. Turn right on the gravel road and travel a half mile to the refuge office.