Muleshoe NWR is the oldest national wildlife refuge in Texas. It was established by Executive Order on October 24, 1935. Located on the high plains of west Texas, Muleshoe was established as a wintering area for migrating waterfowl and sandhill cranes.

Directions to the Headquarters:

From Muleshoe, Texas: Take Highway 214 south 20 miles. Go west on Caliche Road for 2.25 miles to refuge headquarters. From Morton, Texas: Take Highway 214 north 18 miles. Go west on Caliche Road 2.25 miles.

Directions To the Refuge: From Muleshoe, take Highway 214 south 20 miles. Go west on Caliche Road for 2.25 miles to refuge headquarters. From Morton, take Highway 214 north 18 miles. Go west on Caliche Road 2.25 miles.