Millwood is located in the southwest corner of Arkansas on the Little River, 16 miles upstream from its confluence with the Red River. Nine recreation areas offer modern camping facilities. Millwood Lake provides some of the best fishing in the country, while the surrounding land is prime habitat for nature enthusiasts of all types. Birders from across the nation come to Millwood to get a glimpse of the over 309 bird species making appearances throughout the year.

From Texarkana, 16 miles north on US 59-71, 9 miles east of Ashdown on AR 32.